News

2022-06-01 BREAKING NEWS – Team Construction: proud to announce that Professor Giuseppe Castellano agreed to be part of the Scientific Advisory Board of IRIDEA

  • Chief of Nephrology, Dialysis and Renal Transplant Unit
  • Associate professor of Nephrology
  • Department of Clinical Sciences and Community Health
  • University of Milan Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Milano Italy

2022-05-20 Experimental drug product ready for the next pharmacodynamic study!

2022-05-13 dose-dependent pharmacology studies completed: We have completed pharmacology studies in rats at three dose levels. One of our lead compounds shows by subcutaneous injection a rapid absorption into the blood stream in about half hour (maximum blood concentration) and a slow elimination from the blood stream with a half-life of about 3 hours. A linear dose dependent behavior of pharmacokinetic parameters is also observed. The AUC0-inf is 1h mg/L per unit dose, indicative of a good body exposition to the drug.

In the dose range 20-60 mg/kg, no adverse event was observed. This concentration is much above the expected therapeutic dose
(6 mg/kg), indicating a wide therapeutic window when administering our lead compound by subcutaneous injection.

2022-05-09 Comparative pharmacology studies completed: we have completed the comparative pharmacology studies in rats. One of our lead compounds shows a bioavailability of 86% by subcutaneous injection. The half-life is of about 3 hours and a there is a very good drug exposition by this administration root.

The subcutaneous injection is a very simple and comfortable administration root that could also be performed at home without the need of hospitalization or nursing. Automatic autoinjectors would further help the drug administration.

2022-03-22 New operational headquarter: IRIDEA is going to move to the Centro Servizi Metrologici e Tecnologici Avanzati (CeSMA) at University Federico II (Naples)

2021-06-17 – Team construction: proud to announce that Gerardo Pietropaolo – accountant and auditor, tax and labor consultant – agreed to be part of the Team of Iridea. He will be responsible for bookkeepping and accounting

  • Gerardo is M.S. in Economics, University of Naples “Federico II – Italy
  • Accountant and Auditor, tax and labor consultant since 1999
  • Consultant of the “Bioteknet Regional Center of Competence”
  • Consultant of “Molecular Diagnostics and Pharmaceuticals Consortium”
  • Consultant of the “Technological District Campania Bioscience”
  • Consultant of the “Meditech Consortium – Mediterranean Competence Centre 4 Innovation”

2021-06-01 – Team construction: proud to announce that Isabel Cabruja – 30 years work experience in Clinical Diagnostics, Analytical Chemistry, Business Development, Market Research, Market Trends, Life Sciences, Product Development and Positioning, Research and Development and Technology Transfer – agreed to be part of the Team of Iridea. She will be responsible for the business development activities of Iridea

  • Isabel is BS in Sciences
  • Specialized in Infectious Diseases
  • Expertise in diagnostics of Newborn screening disorders.
  • 30 years experience in Clinical Diagnostics, Analytical Chemistry, Business Development, Market Research, Market Trends, Life Sciences, Product Development and Positioning, Research and Development and Technology Transfer

2021-05-19 – Team construction: proud to announce that Giovanni Castaldo – Managing Director at Citi – agreed to be part of the board of Iridea

  • Giovanni is Managing Director at Citi, within the Italian Financial Institution Group in Milan, having joined the bank in 2011
  • In 2019 Giovanni has been appointed Head of Italy M&A
  • Previously, Giovanni has been part of the FIG teams of Banca Leonardo, Vitale & Associati and Deutsche Bank
  • He has graduated cum laude in Business and Economics at Bocconi University, Milan
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